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Answers - Using Permanent Ink Markers on CD's & DVD's
The easiest way to label a CD-R is to whip out that permanent marker and write directly on the disc. It's also a great way to assure that the disc won't be readable later on.
The damage won't happen today, or even next month, but at some point the ink will leach into the reflect
The damage won't happen today, or even next month, but at some point the ink will leach into the reflect
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
ive layer of the disc and it'll be the end of your data.
Now, we're not saying you can't label your discs. But you do have to be careful of the kind of writing instrument you use to do so. In order to understand why certain markers and pens can harm your CD-Rs and DVDs, we first
Now, we're not saying you can't label your discs. But you do have to be careful of the kind of writing instrument you use to do so. In order to understand why certain markers and pens can harm your CD-Rs and DVDs, we first
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
need a basic lesson on the physical properties that make up the disc:
CD-Rs and DVDs are made mostly of polycarbonate substrate, or plastic. The plastic is there to carry the data layer - the shiny metal you can see when you look at the bottom of a disc. The data appear as mark
CD-Rs and DVDs are made mostly of polycarbonate substrate, or plastic. The plastic is there to carry the data layer - the shiny metal you can see when you look at the bottom of a disc. The data appear as mark
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
s or pits that either absorb light from the laser beam or transmit the light back to the laser/photosensor by way of the shiny metal reflective layer.
Most people know that it is very important to keep the bottom of your discs clean and scratch free. Scratches, fingerprints, and
Most people know that it is very important to keep the bottom of your discs clean and scratch free. Scratches, fingerprints, and
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
other debris can stop the laser from reading the data.
However, most people don't realize that the tops of discs are just as prone to damage as the bottom - if not more so! Although you can physically see the shiny data layer from the bottom of a CD-R, it is actually applied to
However, most people don't realize that the tops of discs are just as prone to damage as the bottom - if not more so! Although you can physically see the shiny data layer from the bottom of a CD-R, it is actually applied to
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
the TOP side of the disc, just under the label. On some CD-Rs, the data layer is under nothing but a thin layer of lacquer. Damage to the top of the disc can destroy the data all together.
There are a few side notes that we cannot ignore here: The first being that CD-Rs and DVD
There are a few side notes that we cannot ignore here: The first being that CD-Rs and DVD
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
s are constructed differently. The data layer in a DVD is more protected than that of a CD-R. However, this does not make it immune to damage.
Second, it should go without saying (but we'll say it anyway) that you should never write on or label a double sided DVD - since both si
Second, it should go without saying (but we'll say it anyway) that you should never write on or label a double sided DVD - since both si
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
des are read by the laser.
Last, some CD-Rs have additional protective layers on the top of the disc, for example those with a "white printable surface." These CD-Rs, while more expensive, are far less susceptible to damage.
So what harm will come from writing on discs? Obviou
Last, some CD-Rs have additional protective layers on the top of the disc, for example those with a "white printable surface." These CD-Rs, while more expensive, are far less susceptible to damage.
So what harm will come from writing on discs? Obviou
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
sly, ballpoint or hard tipped pens can scratch the surface of the disc where the data reside, possibly rendering it unplayable. Anything that puts high point-pressure on the surface can damage the delicate layers beneath. Although this might not happen every time, it would be wor
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
th not taking the risk.
But what about those soft tipped permanent markers that everyone uses? Can those cause harm, too? Possibly. The tip won't harm your disc, but the ink might.
There is growing concern that components of ink from markers previously thought of as "safe," suc
But what about those soft tipped permanent markers that everyone uses? Can those cause harm, too? Possibly. The tip won't harm your disc, but the ink might.
There is growing concern that components of ink from markers previously thought of as "safe," suc
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
as many commonly used permanent markers, will eventually penetrate and be absorbed by the inner layers of your disc, damaging the surface where the data is stored and rendering the disc unplayable.
Use of permanent markers
Various postings are surfacing across the internet fro
Use of permanent markers
Various postings are surfacing across the internet fro
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
m professionals and hobbyists alike, reporting that over time permanent ink has made their properly stored discs unusable. There is no apparent reason for the corruption other than the ink used to label the disc.
So what should you do? Consider the purpose of the disc. If all y
So what should you do? Consider the purpose of the disc. If all y
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
ou're doing is making a music disc for your car, it really doesn't matter. You'll have a new favorite band before the ink has time to ruin it. However, if you are archiving precious family memories or other highly important data, don't write on top of that disc!
Instead, label t
Instead, label t
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
he disc where no data is recorded. The inner hub area, though small, is a perfect location for labeling.
Alternatively, if you didn't use the entire capacity of the disc during recording, you can write in the area that wasn't burned. Discs are written from the inside out. The ar
Alternatively, if you didn't use the entire capacity of the disc during recording, you can write in the area that wasn't burned. Discs are written from the inside out. The ar
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
ea that was recorded is darker. The lighter area wasn't recorded and has no data, so it's safe for labeling. But, be careful that you don't cross over the line and into the data (see illustration). Note: Don't do this with rewritable discs.
Write in the area that was not burned
Write in the area that was not burned
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
If you really want to be safe, use a specially formulated disc marker. It contains ink specifically made for labeling the tops of CD-Rs and DVDs.
What do I do if I have already labeled my discs with a permanent marker? Transfer the data to a new ink-free disc as soon as possib
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
le.
Don't even think about trying to remove the ink. Permanent ink and the soft porous resin of a disc are quite happy together, and don't want to be separated. Attempting to remove the ink will most certainly ruin the disc.
According to the National Institute of Standards and
Don't even think about trying to remove the ink. Permanent ink and the soft porous resin of a disc are quite happy together, and don't want to be separated. Attempting to remove the ink will most certainly ruin the disc.
According to the National Institute of Standards and
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
Technology (NIST), a properly cared for disc which is stored under recommended storage conditions can have a very long life expectancy. NSIT's research has concluded that CD-R, DVD-R, and DVD+R discs should have a life expectancy of 100 to 200 years or more. CD-RW, DVD-RW, DVD+RW
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
, and DVD-RAM discs should have a life expectancy of 25 years or more. Less testing has been done for CD-ROM and DVD-ROM discs, however lifetime expectations vary from 20 to 100 years for these discs.
One thing is certain - proper care of any disc will extend its life.
Comments
One thing is certain - proper care of any disc will extend its life.
Comments
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
?
We'd love to hear from you. Give us some feedback about this article or tell us about your CD-R experiences. Email us at: comments@tapeonline.com. To read the article and see the illustrations, visit www.tapeonline.com
We'd love to hear from you. Give us some feedback about this article or tell us about your CD-R experiences. Email us at: comments@tapeonline.com. To read the article and see the illustrations, visit www.tapeonline.com
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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