Answers - Real Estate

Curb Appeal More important than you think. First impressions count. If buyers are put off from the start, they may not even bother ringing your doorbell. Same principles as indoors. Tidy up!
- Remove any litter or piles of leaves
- Weed the

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

garden, plant a few seasonal flowers, add a tub or hanging basket
- Does the hedge need trimming?
- Is the fence in good condition?
- Does the gate need oiling, or painting?
- Does the front door need painting?
- Can you see t

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

e number of the house from the road?
- Is there anything you can do to improve your neighbour’s front gardens? Carefully and gently (!) offer to mow their lawn, trim their hedge, lend them a tub of flowers.

Make your house look the best on th

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

e road.

Inside Look at your house as if you were a buyer seeing your house for the first time. The entrance and first room are very important; buyers often get turned off within the first few minutes.
- Finish off any DIY projects. (If you can’t

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

face it, get someone in to do it!)
- De-clutter! That famous phrase! The longer you’ve lived in your house the more clutter you’ve probably accumulated. Look at your things as if you were packing to move.
First: Sort out the loft and/or gara

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ge – are you really going to use that half tin of paint? Will you ever get back on to your exercise bike? Will you ever fix the rusty lawnmower? Be ruthless. Are you really going to take it with you to your new house, after all, you are supposed to be

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

oving house, right? Now that you’ve got extra storage space, use it! Have a look round the rest of your house and check for things that you want to keep, but probably don’t use very often. They can go into boxes and be stored. If you run out of space,

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

there are storage spaces to rent nowadays, or ask friends and relatives. You can always do a car boot sale, put it on eBay, or give it to the charity shop. Or even throw it away! Its very good feng shui to be de-cluttering, letting go of old, usel

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ss and broken things allows new energy to come into your house and your life. Packing is an awful job, but if you’re serious about moving you’ll have to do it one day soon, so why not make a head start?
- Clean, clean + clean again! Your house ca

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

n never be too clean! Do all the corners you never usually to do, the windows (inside and out), wash the nets or curtains, shampoo the carpets, and send the dog to be groomed! They say the appealing smells are coffee and fresh baked bread, but even th

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

t won’t mask the smell of dirty bathrooms. In my book nothing beats the smell of polish and bleach! Again why not get a cleaning company to do this for you? Might seem an extravagance at the time, but a team of 4 cleaners could whiz through your house

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

n a day and do all the jobs it would have taken you weeks to do. Then all you have to do is keep it tidy!
- Tidy. Sounds obvious. Buyers aren’t going to look inside your cupboards on a first visit, so put ‘stuff’ away! So make sure your ‘surfaces’

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

are clear. Fold your towels, make your bed, do the washing up
- Have a hard look at your kitchen. This is often the most expensive room in the house to ‘replace’, from a buyers point of view, so the last thing you want is to give them the impres

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ion your house needs a new one. Clean. Perhaps redecorate, a fresh coat of paint might be all it needs. Does it smell of cooking? Old, lingering cooking odours are very off putting.
- The next potentially off putting room is the bathroom. Sorry to

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

say it again, but clean!! If your bathroom has mould growing on it, and a certain odour, buyers will think ‘new bathroom’ rather than ‘a good clean’
- Have a look at your furniture? Are you taking that saggy old sofa to you new home? No? So get r

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

place it with a new one (suitable for your new home) now.
- Does every room have a purpose? And is it doing its job? Junk rooms are not allowed; turn it back into a guest bedroom!

Myself, I don’t believe in completely de-personalising your ho

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

use. People want to buy a home not a show house. So its ok to have a few family photos on the mantelpiece and some of the kids ‘art’ on the fridge; but note the word ‘few’! Be selective and pack the rest away.

The Garden

People want more from their g

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

rden these days. It used to be OK just to have a lawn. Nowadays people expect an outdoor room. Firstly, get the basics right. I'll say it again, tidy! Mow the lawn. Weed. Get rid of the pile of grass you're pretending is a compost heap!

Then think

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

about the size of your garden and the people you want to sell your house to. Adding a patio with table and chairs always looks appealing. Is it safe for children to play in? Next do some planting.

If you know you're going to move in a few months ti

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

e, plan ahead - find out which flowers will be in bloom at that time and plant them now. If you can't do that, add some tubs and hanging baskets. A splash of colour always looks cheerful and makes a good impression.

Remember: first impressions count

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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