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10) No state income tax. Thus far Nevadans have resisted the urge to whine and ask government to meet their personal

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

needs, and we have managed to make even the mention of a state income tax a form of political suicide. We absolutely r

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

b people blind at the Motor Vehicle bureau instead.

9) Everything is open 24 hours. Grocery stores, gas stations, fa

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

t food joints, you name it. If you need it late at night, in Las Vegas you can get it fast.

8) You can buy liquor at

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

the grocery store. No special licenses or permits needed. It’s convenient this way. See what can be achieved when i

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

’s ok for the politicians to be alcoholics? Things get easier.

7) The restaurants. Oh my god, the food here is amaz

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ng. You can go to a different topnotch restaurant every night for a year and then start over and order soemthing diffe

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

rent. In fact, I started doing this in 1986. I’m only half way through the menus. They keep building more restaurant

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

! And the buffets! It’s easy to gain weight in this town.

6) The weather. The weather? Are you kidding? On a giv

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

n day in July its 167 degrees in my car! So what the sun shines 340 days a year. It’s freaking hot! Oh, and we lie.

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

Whatever the temperature is on the news in the summer, add 9 degrees for the real temperature. 111? No, 120. Trust me

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

.

5) The women. There are more beautiful women here per square inch then anyplace else in the entire universe. Why,

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

you ask? Not sure, but it might have something to do with the bushel baskets of money that get thrown around here on a

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

daily basis.

4) The men with the money. There here chasing after all the beautiful women. Or is it the other way aro

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

und?

3) The architecture. Yes, Las Vegas continually breaks new ground in building design. Basically, we just steal

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

themes from other unique and beautiful cities, build cheesy replicas, and get you really drunk when you show up. You g

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

nna argue with success?

2) The clean air. Well, it used to be clean, but all those visitors from California who neve

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

r breathe anything they can’t see came here and brought their smog with them. Keeping you drunk works here, too.

1)

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

nd the number one reason living in Las Vegas is a blast is…

Drive a few minutes from anywhere in town, and you are cru

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

sing down the Las Vegas strip.

People come from all over the world to get here. I came 4.3 miles.

Eat your heart out

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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