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If you are relocating to Anaheim, California, welcome to Disneyland! With its theme parks, sports teams and convention center, Anaheim thrives on tourism as a rap

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

idly growing city.

In Orange County, California, the city of Anaheim is part of a large metropolitan area. Primarily urban population, recent estimates have 342,

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

410 living in the city. Add the outlying communities, and nearly 3,000,000 people reside in the metropolitan area. The population density is high with over 67-hun

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

dred people per square, revealed by U.S. Census Bureau statistics in 2000. The Hispanic race was well above the state average, accounting for 46.8% of the populat

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ion. White non-Hispanic residents totaled 35.9%, Asian (12%) and Black (2.7%). The foreign-born population in Anaheim is significantly above average for Californi

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

a. Low is the median age of residents at 30 years.

If you are relocating to Anaheim, you’ll find it’s not difficult to find work. As of early 2005, Orange County

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

’s unemployment rate was the lowest in California. Demographics vary greatly within the city with Anaheim Hills’ residents averaging $120,000 of household income

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

annually. On the west end of the city the average income is $38,000 where the population is predominantly Hispanic and black. But poverty levels are still low. Ab

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

out 10.4% of families and 14.1% of the population were below the poverty line. Anaheim also ranks as one of the safest cities for its size. The crime index in 200

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

5 was 281.4, much lower than the national average of 325.2.

Anaheim is the largest and wealthiest city in Orange County. Most important to the economy is tourism

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

. It’s no surprise that the largest employer in Anaheim is Disneyland with its theme parks employing an estimated 21,000 people. Disney operations pump $3.6 billi

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

on of revenue into the community annually. When Disneyland opened in 1955, Anaheim had only 87 hotel/motel rooms. Today travelers can count on nearly 20,000 place

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

s to stay. Another vital part of the tourism industry is the Anaheim Convention Center, home to many national conferences. Put it all together and Anaheim is one

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

of the top convention and vacation destinations in the country.

With very little rainfall, summers can be moderate to hot. Winters tend to be mild and dry. Avera

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ge temperatures between January and July do not differ greatly at 57 and 74 degrees, respectively. Annual precipitation is 11 inches on average. Anaheim is relati

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

vely flat except for newer residential areas on rolling terrain at the foothills of the Santa Ana Mountains. If you are relocating to Anaheim, you won’t be far fr

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

om the Pacific coastline, just 13 miles away. Also close by is the college campuses at Fullerton, Santa Ana and University of Phoenix-Southern California. Combine

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

d the three colleges provide higher education to well over 40,000 full-time students.

Travelers to Anaheim primarily use Los Angeles International Airport (LAX)

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

located just a half hour away. LAX) is the third busiest airport in the world. Santa Ana's John Wayne Airport, just 16 miles from Anaheim, is smaller but dependab

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

le for its domestic travel. Metrolink, a regional commuter rail system, and Amtrak serve the city as does Greyhound with daily bus service to many U.S. locations.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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