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Old Southern charm and hospitality are the trademarks of Savannah, a mid-sized city in Georgia. Thanks to its warm climate and affordability, many people now relocating to Savannah are usually of retirement age.

Savannah

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

borders South Carolina where the Savannah River and the Atlantic Ocean become natural boundaries. Encompassing 75 miles of land, the citizenry has been dwindling in recent years. The population was estimated at 128,453 r

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

esidents in 2005, a 2.3% decrease since the 2000 U.S. Census. During the 1990s, the city lost another 4.7% of its people. Savannah is not as densely populated as other big cities in Georgia. One of the largest African Ame

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ican communities in the state is found here, with over 60% of the city’s population. White Non-Hispanic residents account for another 34%. According to U.S. Census statistics, the median age of residents was 32 years, 4.4

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

years younger than the U.S. average. In the city, families made up 59% of city homes that averaged 2.4 occupants.

The take home pay of Savannah’s workers is very low. Both median household and family income averages wer

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

over $15,000 below the national average. The annual household income was $30,887, compared with the U.S. average of $46,242. A good many retirees relocating to Savannah benefit from Social Security, with about 30% of cit

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

y households already drawing that income. Savannah boasts low unemployment rates, as job growth is small but steady with a 3.1% increase in 2005, primarily in the service sector. As of 2004, the highest number of jobs for

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

women was in health care, at 19% of the female job force. Construction was top of the list for men making up 13% of their jobs. As a right-to-work state, the average take home pay is low. The recent focus of job creation

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

has been in hospitality, port services, tourism and convention, and information technology. Poverty is high with 22.8% of Savannah’s people considered poor by government estimations.

Manufacturing is the largest part of

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

Savannah’s economy with plants like Gulfstream Aerospace, International Paper, and Georgia Pacific. With the city’s history and charm, tourism has grown rapidly with roughly six million visitors annually, adding more than

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

$1.5 billion to the economy. Savannah also supports a military community with Hunter Army Airfield located within city limits. The army complex is part of an infantry division located at Fort Stewart, 40 miles away. Toget

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

her, the installations find 22,000 soldiers and 3,500 civilians on government payrolls. With its seaports and cargo hubs, the Port of Savannah is the fifth largest container port in the country. Designated a Foreign Trade

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

Zone, the port is a major distribution point.

The French revere Savannah, dubbing it "The most beautiful city in North America," in Paris's famed Le Monde newspaper. People relocating to Savannah flock here to experienc

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

the city’s mild climate, old world charm and atmosphere, moderately priced accommodations, and unique historic downtown district. Savannah is attracting retirees, too, who are usually looking for alternatives to an incre

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

asingly crowded Florida. A relatively inexpensive town in which to live and do business, the cost of living index is slightly below average. Housing can be affordable, with the median house/condo value at $108,100 in 2005

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

Two-thirds of the city is made up of single-family homes. The median monthly housing costs for mortgaged owners was $1,052, while rent averaged $717 per month.

Savannah’s waterfront remains open to development. Located

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

near the central business and historic districts is a large tract of land. Developers have already located a large convention center and resort here. Serious crimes like murder have traditionally been high in Savannah. Ho

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

wever, the city had seen a decline is criminal activity is recent years. The FBI Crime Index report for Savannah in 2004 showed a number nearly double the national crime rate. Hot and humid describe some days in Savannah,

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

but frequent afternoon showers in summer help beat the heat. With a semitropical climate, the city stays warm. Historically, there are seven months of the year when the average temperature is 70 degrees or higher. July av

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

erages 81.2 degrees, while January is 49.2. The average annual rainfall is 49 inches. Savannah-area historical tornado activity is significantly below Georgia state average. It is 39% smaller than the overall U.S. average

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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