Answers - Real Estate

You might be thinking of taking a home equity loan to do some home improvements or con

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

solidate debt. Many of these equity loans come in the form of a home equity line of cr

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

dit (HELOC). While often a great option for you, here are some things to ponder while

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

eciding:

Pros

1. Take the Money As Needed

HELOCs provide you with financial

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

flexibility and time to make smart decisions. For example, if used for long term home

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

mprovement projects, you can take the money in installments only when you need to buy

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

more materials or pay construction costs. This is a nice alternative to lump-sum secon

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

mortgages where you take the money all at once and have to begin repaying on the tota

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

immediately.

2. Consolidate High Interest Debt

These equity loans give you t

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

e chance to consolidate much higher interest credit card debt into a lower monthly pay

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ent. This can provide you with some financial relief. When you pay enough of the equit

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

y line off, you can always take out more to tackle other needs.

Cons

1. Your Hous

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

Is At Risk

Like any other lien against your property, failure to make payments c

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

n cause your home to go into foreclosure. Before consolidating debt or taking on home

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

mprovements, you will want to carefully consider whether this is a risk worth taking.

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

2. HELOCs Have High Variable Rates

Since secondary liens are riskier to lender

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

s, they will charge you higher rates than on conforming first mortgages to compensate

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

or that threat. Also, these rates are frequently adjustable rates tied to the prime ra

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

e. This can be dangerous for you, especially if you are consolidating debt and still u

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ing the cards.

These ideas should help you decide if this is the right choice for you

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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