Answers - Real Estate

It's like this: You buy a house for a price, and they thrown in buyer's remorse for free.

I'm

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

not sure about you, but just within seconds of buying, say a pair of shoes or an ice cream, I

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

regret the decision and wish I'd spent the money on something wiser (i.e., a book). Of course

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

, I’m just being hard on myself.

But when we think about really big purchases, such as that d

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

eam house that cost you sweat and blood, that perfect real estate you've been searching for so

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

long and which you thought was just fiction--when you think about it, then it's perfectly nor

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

al to let "buyer's remorse" set in you. After all, you want only the best home for you, and y

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ou want to be sure you made the best decision.

Even if you've planned ahead, visited a hundre

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

homes to choose from, and created the most comprehensive pros and cons list, buyer's remorse

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

is sure to come. And it's a healthy reaction. Doubt makes you double-check things, and that'

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

good because there might really be something awry about your new home you overlooked.

1. If

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

he house reveals more repair issues than you’re willing to take on;

2. If there are problems

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

with the deed;

3. If the house doesn't appraise at a price at or above the contract;

4. If y

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

u're short in finances;

Then your buyer's remorse may be valid. If you can still legally bac

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

k out of the contract, that's fine. It just means the house wasn't meant for you, and the sea

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ch starts all over again.

But let's put it this way too. Once you've eliminated all the poss

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ible culprits of your remorse, and decided the house is just fine and it's just you--start fal

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ing in love with your house again. Remember all the good qualities that made you stand out in

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

the first place. Then, consider all the laughs and milestones you and your family will share

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

there. Sure, the uncertainty of newness is scary, but love and ice cream will get you through

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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