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  • Answers - Questions to Ask Before Making an Offer

    Are you in the market for buying a new home? Have you found a home you like and are thinking about placing a bid? Before you do, there are a series of
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    critical questions you should ask. You should ask not only the homeowner, but the realtor as well. It is likely that you will get different answers fro
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    m both. However, you should be able to grasp a solid idea of what the truth actually is based on the information you receive from both sources. Answers
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    o these questions will not only allow you to decide whether or not to make a bid, but how much you should offer.

    Below are the question to ask...
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    >
    -- Approximately how long has the house been on the market?
    If the house has been on the market for a long time, it is likely that
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    the seller is having a hard time selling the home. This can be a result of a bad market, or because their price is just too high. Therefore, always star
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    t with a low bid.

    -- Have there been any price reductions to the asking sale price?
    Reductions usually mean that the seller is ver
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    eager to sell the house and has become more aggressive by lowering their asking price. It is likely that they are also recalculating the actual worth o
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    f their home.

    >-- Have there been any offers made on the house already? How many? What happened to these offers?
    If the answer is 'y
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    s, there have been offers made', find out what happened. Were these offers declined? Accepted? Did the deal fall through? If there were offers that were
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    rejected, don't worry. This does not mean that your offer is going to be declined. The owner may have changed their mind-set as to what they expect to
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    get for their house and will be willing to accept a previously declined bid.

    -- How long have the current sellers been the owners of the house?
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    If the owners have only been in the house for a few years, say three or four, then there is likely less room for negotiating a sale price. This is
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    because the price they bought the property for is not going to be much different that what they are asking. However, if they did home improvements to the
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    ouse, then they will be able to get more money. How much more will depend on how much work and what kind.

    If the owners have owned the home for a long
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    time, then there is a great deal of room for negotiating the price. The price they originally paid is going to be very different than today's market. Th
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    ir profits are going to be high regardless. Its just a matter of what they are willing to accept.

    -- Have any home improvements been made to the resid
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    ence?
    This will affect the sale price. However, some home improvements are going to be valuable to some, but not others. For example, new windows
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    will increase the value of a home no matter who is buying. On the contrary, a new pool will be worth as much as it is considered valuable to the buyer.
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip

    Learn more about the process of making an offer on a new home purchase


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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