Answers - Real Estate

Whether you're buying your first home or your 21st home, it's never easy to find exactly the right house. Finding your dream house requires

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

patience and persistence.

Let's be honest. Buying a house is an emotional decision, as well as a rational, financial one. Take my friend Tr

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

na, for example. Trina was house hunting one day in the early spring when her broker showed a house with daffodils blooming by the front doo

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

r. Trina instantly fell in love with the house, despite the fact that it had 2 bathrooms instead of 3, and a den but only 3 bedrooms. It als

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

had a formal dining room, not the great room that Trina really wanted. But, it had daffodils blooming by the front walk. Trina and her husb

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

nd bought the house, and started expensive renovations. Five years later, they have the house they've always dreamed of, but at a price.

"L

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ooking back, it would have been a lot cheaper for me to find a house with all the features that we needed, and plant daffodils!" Trina says.

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

It's important to know exactly what you are looking for, when you buy a house. If Trina had made a list of her wants and needs before she s

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

tarted house hunting, she could have saved herself years of noisy, messy renovations.

Before you open the real estate section of a newspape

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

, or contact a real estate agent, sit down with a pencil and paper and make a list of your wants and needs. If you are buying the house with

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

someone else, have them make their own separate list. Then, compare the two.

The first question you need to ask is, "What do I need in a ho

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

use?" For Trina, the answer was 4 bedrooms and 3 baths in her children's current school district. With the birth of her third son, the famil

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

had simply outgrown their current home.

Your list of needs might be totally different. Maybe you need a house on one level, so that you wo

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

n't have to climb stairs. Maybe you need a big, sunny kitchen, a spacious family room, or a yard large enough for soccer. Maybe you need an

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

rea with no restrictions on having a home-based business.

Next, ask yourself "What do I want in a house?" Maybe you'd love a great view, o

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

en, sunny rooms, cathedral ceilings, a fireplace, a walk-in closet or solar heating.

Finally, ask yourself "What do I hate?" Make a list of

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

the features that you will not accept in your new home. For Trina, Tudor-style architecture is high on that list. "Our old house was Tudor

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

tyle. It was so dark, and the rooms were so ugly, that I soon hated it!"

Now, compare your list with your partner's. Are there items that b

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

oth of you want or need? That's a good start. Are some of your "hates" on your partner's "wants" list? If so, you'll need to discuss it and

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ompromise.

Finally, create a master list with all the needs, wants and hates for the two of you as a couple. This is your home buying guide

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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