Answers - Real Estate

Whether you are buying or selling, closing a sale can be costly. There is a lot to think about above and beyond what the mortgage payments will be.

Firstly, there's the down

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

payment. The more you can afford, the less your loan will be, but while the standard minimum required used to be about 10%, many new programs are available that allow the buye

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

r to have only 0-5% down. Keep in mind that with no money down you will need to have an amazing credit rating and Private Mortgage Insurance (PMI) will be required. For the le

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

nding institution to determine your credit, you must pay a fee of around $50. A tax company may be contacted to verify that you have payed your taxes, and this is another roug

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

hly $75.

Sometimes there is a lenders fee, roughly 1-3% of the total loan, so talk to your loan agent about this. If you need the home you are buying appraised so that your l

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

oaning institution can determine the loan amount, this appraisal fee can be at least a few hundred dollars and sometimes as much as $1000. If you are assuming the sellers mort

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

gage, there may be an assumption fee of a couple hundred dollars or up to 1% of the total loan amount.

Whether buying or selling, you may want the home to be inspected for va

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ious things. The advantage for sellers is that this is reassuring to buyers and can speed the selling process. The advantage for buyers is that they will then know exactly wha

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

t they are getting, and their lending institution may require it before granting the loan, or as part of the market evaluation. Some examples of what may need inspecting are p

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

roperty inspections, including a check of the foundation, construction, plumbing and electrical system. These generally cost a few hundred dollars. A roof inspection is often

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

done separately for about $100 or less. If the area the home is located may be on a fault line or a landslide area, geological inspections are recommended. You may also want t

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

o have the home inspected for pests such as termites or carpenter ants, things that threaten the structural integrity of the home. This can generally run around $100 or more i

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

f the home is very large. If the home is on a septic system, it is a good idea to get this checked as well. Septic inspections are surprisingly expensive, running at an averag

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

e of a few hundred dollars. But imagine the alternative of discovering a problem after you've moved in.

If the home is older, testing for asbestos, radon or lead may be impor

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ant. You want to ensure your home is as safe as possible for your family.

Then there are various insurance costs. In addition to mortgage insurance, you might consider extend

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ed title insurance. This covers any liens that may have been unrecorded, and may be required by lenders. It is based on a percentage of your loan amount.

Don't forget the var

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ious taxes. Your municipality may have a tax based on the final price of the home. If you are a veteran you should be exempt from this tax.

While all of the prices listed abo

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ve are relative, it is important to keep in mind that there will be extra fees associated with the closing process. If you are buying, you may be able to negotiate with your r

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

eal estate agent to have the seller pay closing costs. However there may be a limit that they are willing to pay, so make sure this is negotiated completely beforehand, and re

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

alize any inspections you decide to conduct after your negotiations will be at your expense. This is one reason for a thorough examination of the home before you make an offer

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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