Answers - Real Estate

In South Africa, each property has a title deed and all property transfers are registered in the Deeds Office. The title deed contai

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ns all the information with regards to a particular property, such as the erf number, property address, owner’s details, mortga

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ge (if any) as well as servitudes and restrictions. A copy of the title deed of each property in the country is kept in the Deeds Of

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ice. The original title deed document is in the possession of the owner or financial institution holding a mortgage over the propert

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

y.

Most potential property buyers (especially foreigners and first-time buyers) are not aware of the existence of the title deed and

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

the process of transferring a property or the role of the Deeds Office in the process. Those that are aware of title deeds, often h

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ve heard of it but perceive it as some phantom document, lost in the archives of a governmental department. Very few potential buyer

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

s know that these documents are extremely important and that they have a right to see the title deed of any property they are interes

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ted in buying.Can you imagine the frustration of a new property owner who wants to extend the house he has just bought, but finds out

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

that he can not add even one more room to the house, due to restrictions on his title deed? Another example is of a couple who recen

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

tly bought a very large property with the idea of creating a breathtaking garden. They were told that an underground river exists, r

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

unning across their property. When they bought the property, it was with the express idea to sink a borehole in order to have suffic

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ent water for their planned garden. After transfer has taken place and they have moved in, they found that there is indeed water in

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

an underground river and that the cost in sinking a borehole would be minimal, as the water is fairly close to ground level. As far

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

as they were concerned, their dream was coming true – until they found out that they can not sink a borehole on their property,

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

due to restrictions on the title deed!Property buyers should always ask their agent for a copy of the title deed of the property they

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

are interested in buying. Read it carefully and ensure that there are no servitudes or restrictions which might impede on your idea

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

s with regards to the property. If you plan to extend the existing building, look at the building restrictions. Should your plans i

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

clude running a business from the property, determine the zoning of the property and ensure that your specific business can indeed be

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

run from that property. Buying a property without seeing the title deed first, could be a serious mistake on any buyer’s part

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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If you're considering creating cable advertising to promote your company, products or services, you'll want to avoid advertising that will actually damage your brand in the marketplace. Danskin warns of common pitfalls, and provides steps to successful cable advertising results.

Sales people are trained to get you to sign right then and there. They know that the chances of you committing to a purchase dwindle as time elapses. Don't fall for this dirty tactic, instead counter it and bring the issue of fairness back into perspective.

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Answers - Property Buyers Tip – Look at Title Deed of the Property

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