Answers - Real Estate

Today's log homes are built for strength, durability, energy efficiency, and, of course, uni

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

que beauty. To provide all of these benefits, the logs should be milled or hand cut have a t

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ight fit during construction and kiln-dried to reduce moisture content, rem

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ove mold and fungi, kill any insects, and stabilize the wood.

All wood gives off moisture u

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ntil there is an equilibrium reached within the cells of the wood. As this equilibrium is re

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ched, the dimensions of the log will change (the logs will shrink). A log home built from ai

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

r dried, green, or standing-dead (not kiln-dried) logs is expected to settle as much as thre

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

e inches per eight feet of wall height. Instructions are given to the homeowner as to how to

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

adjust the walls with jacks, bolts and other mechanisms every few years. Doors may stick, f

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

loors may become unleveled, and roofs may sag. This is what can be the case with log homes b

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ilt with logs containing a high moisture content. True kiln-drying eliminates these problems

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

and the need for the adjustments.

Proper Kiln-drying logs during the manufacturing

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

process will:

* Stabilize the wood

* Expose checks in the wood (it will ha

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ppen anyway) allowing the turning of logs during milling to place checks in un-obtrusive pla

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ces creating a better finish

* Kills wood boring insects (beetles) and decay fungi<

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

r>
* Produce a lighter log saving cost of transportation and ease construction

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

* Creates a better surface to accept stain and finishes

If your log manufact

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

urer says they kiln-dry, make sure they

Kiln-dry for at least 30 days
<

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

b>Temperatures reach 180 degrees
Logs are monitored and then sample cut and weig

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

hed
Logs not meeting the moisture level needed are dropped out of the process

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Answers - Why Look for Kiln-Dried Logs When Building a Log Home

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