Answers - Real Estate

It is a given and certainly appreciated and understood that your property is used as a vehicle for monetary gain. However, it is imperative that you "live with the

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

rest of humankind on this planet". Do not expect an agent or real estate brokerage firm to sell an apartment for $500,000 which is worth only half that amount on

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

the market, no matter what article you read in the weekend city paper. The responsibility of the agent is to get you the best price they can, but an agent is simply n

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ot capable of raising the real-estate value of your property by one-hundred percent, just because you were told by the aunt of your best-friend's second-cousin, that

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

our specific apartment is one of a kind.

Stay on the planet earth. It is easy to get carried away. We all know how tempting it is to take your property which

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

you and the rest of the world knows is worth only $250K and put it out on the market for $300K hoping to find that lucky break. Stories abound of the lucky "lotto"

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

winner who sold a run-down apartment for $100K over market price. Do not expect to win the "lotto". Pricing yourself out of the market even if you give an agent

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

exclusivity, will just lead to frustration later on. You will be sitting on top of a property you needed to sell six months ago, bemoaning the fact that no one

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ants to offer you just a few thousand dollars more than its market worth, because you smile nicely.

This rule also applies to renting. Agents field many calls askin

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

g us to find a four room apartment in Old Katamon or Bakkah of approximately 100+ square meters with a garden, and in great condition to rent for a budget of $1000

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

a month. Simply put, finding something like this within the budget is just not going to happen. Whenever a reputable agent receives such a phone call, they will simp

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

y try and explain that one must be realistic in expectancies. It does no good to hope you will find some landlord who does not know the worth of his apartment. Some l

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

isten, others insist on wasting a month of their precious time, speaking with brokers who promise anything, and walking away frustrated and mumbling at the horrible s

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

rvice brokers in Israel give to them. Try to be realistic. Try to demand something that is possible. And understand that if it is not possible, brokers will be straig

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

tforward and tell you so.

In selling, price your property, and make the price realistic. Your neighbor on the first floor may have the exact same apartment a

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

s you do, but they will get $15,000 more than you will, because they have six steps to their apartment and you have forty-two. You cannot compare the two apartments e

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

en if they look exactly the same - because they are not the same!

The same holds true for those who want to purchase. Don't negotiate with the owners of the bottom a

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

artment telling them that the exact same apartment is available on the top floor for $15,000 less. You must make a decision. Is that $15,000 worth not having to climb

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

forty-two steps every day?

Please save the trips into the outer limits for your next great novel. Don't try and convince a young couple with two small toddlers that

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

walking up 42 steps is just as good as walking up six steps. It just wont work. Praise the good aspects of your property, but don't run away from the possible defects

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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