Answers - Real Estate

Closely on its tail is Prime Central London, where 120 sq. m. super-luxury apartments can cost ?1,170,000 or ?9,750 per square metre (sq. m.) (in Euro: ?1,742,656, or ?14,522 per sq. m.). Apartments of 120 sq. m. in other luxury areas

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

of Central London are likely to cost ?580,000 or ?4,833 per sq. m. (?863,880 or ?7,199). The large difference is explained by London’s highly segmented top-end market, with super-luxury apartments in absolutely prime areas commanding c

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

onsiderable premiums.

Paris and Amsterdam follow London. A 120 sq. m. apartment in either of these cities has an average purchase price of ?800,000 (?6,667 per sq. m.).

Moscow is Europe’s sixth most expensive capital for buyers of res

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

dential property. And though apartments in Moscow can be rather rewarding for buyers in terms of rental income returns, investors should be aware of the high risks (purchases are cash-based, and the authorities can suddenly turn hostile

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

).

Dublin makes an appearance among Europe’s most expensive cities in 10th place, with a high end 120 sq. m. apartment on average costing around ?600,000.

The Baltics, till recently Europe’s hottest residential investment destination

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

are now expensive. A high-end apartment in Central Vilnius, Lithuania will cost on average around ?3,792 per sq. m (?455,000 for 120 sq. m.). Latvia follows closely with high-end apartments in Central Riga costing an average of ?3,02

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

0 pr sq. m. Rental yields in the Baltics have also dropped to very low levels.

There are still some very inexpensive capitals in Europe. Berlin, in particular (?3,167 per sq. m.), is now experiencing inflows of foreign money in respo

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

se to its relatively low prices. But much less expensive are Slovakia’s Bratislava (?1,292 per sq. m.); Warsaw, Poland (?1,175 per sq. m.); Skopje in Macedonia (?1,125 per sq. m.) and Chisinau in Moldova (?917 per sq. m.). It is to b

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

e expected that foreign buying in some of these capitals will accelerate.

Rental returns are falling

The rental returns on owning apartments in Europe vary greatly - from around 14.13% in Moldova’s capital Chisinau,

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

o 2.43% in Monaco. The trend is for rental income returns to fall, because rents are not keeping pace with prices anywhere in Europe. As 2007 dawns, rental returns are lower in most locations than they have been for 20 or more years.

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

To some extent rental returns appear to correlate with risk. Most of Europe’s ‘high yielding’ countries are in the East. Apartments in four Eastern European capitals earn above 10% rental returns: Chisinau, Moldova (14.13%); Warsaw, P

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

oland (13.28%); Sofia, Bulgaria (10.56%); and Bratislava, Slovakia (10.06%). The higher risks of the East may be a factor in these returns (high corruption, political risks).

But risks are not the only factor. The Global Prop

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

rty Guide believes that the relatively recent arrival of the market economy, high interest rates, and relatively undeveloped mortgage markets. To illustrate, it would surely be hard to label the historic city of Bratislava, Sl

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ovakia, as a high-risk location, yet the rental income returns are excellent.

Western Europe generally suffers from another, different disadvantage: High taxation. There are high rental income returns to be earned in Amsterdam and Pari

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

(8.25% in both), in Munich (7.80%) and Brussels (7.53%). But all four cities are high tax environments.(Poland and Moldova are also high tax for rental income.)

Property in Prime Central London returns surprisingly high rental yields

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

, at 7.13%. Note that this “Prime” category encompasses relatively a narrow group of super-luxury apartments in absolutely prime areas (Belgravia, Chelsea, and Knightsbridge). The high returns in these select locations contrast with the

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

significantly lower rental yields (5.79%) available in Central London’s other luxury areas (Kensington, Bayswater, Notting Hill Gate, St Johns Wood, Highgate, Islington, Highbury, and Primrose Hill).

Rental returns cannot fall

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

forever

Nowhere in Europe are rents keeping pace with the continued rise in property prices. This is cause for concern. At the Global Property Guide, we informally consider a danger signal to be rental retu

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ns of around 4% or below.

Several European capitals offer rental income yields around or below this 4% level. An example is Madrid, where rental returns are now at only 3.15%.

See the tables at: elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

w.globalpropertyguide.com/articleread.php?article_id=82&cid="> http://www.globalpropertyguide.com/articleread.php?article_id=82&cid

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Answers - London and Monaco are Europe's Most Expensive Cities For Residential Property Buyers

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