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Answers - Hidden Problems In Older Homes
"Yikes!"
"Uh-oh..."
The homeowner and I were watching our contractor remove deck boards that concealed an area of a foundation wall that we thought might have settled. The homeowner had noticed a problem when the front door began to
"Uh-oh..."
The homeowner and I were watching our contractor remove deck boards that concealed an area of a foundation wall that we thought might have settled. The homeowner had noticed a problem when the front door began to
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
stick, and an unmistakable settling of the floor under the door had soon followed. The contractor and I assumed that water had caused the foundation to settle, leading to a drop of the floor system - a relatively common problem in ol
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
er homes that is sometimes easily stabilized and repaired.
At this house, however, the problem looked much worse. A large section of the band board - a strip of lumber that surrounds the floor system - was completely rotted. We'd exp
At this house, however, the problem looked much worse. A large section of the band board - a strip of lumber that surrounds the floor system - was completely rotted. We'd exp
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
cted some damage to the band since we were sure that water (the cause of the rotting) was the culprit in the foundation settling. But here the foundation looked intact. It was the band itself that had collapsed, causing the f
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
oor system to drop several inches. Worse yet, the damage extended well into the floor joists.
Ugh. Which one of us was going to give the homeowner the bad news - her minor settling problem in the house she'd recently purchased was ra
Ugh. Which one of us was going to give the homeowner the bad news - her minor settling problem in the house she'd recently purchased was ra
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
pidly becoming a very expensive major repair?
Not Aging Gracefully
Problems in older homes are often well hidden. More often than not, serious damage doesn't show any symptoms until the damage is significant and exp
Not Aging Gracefully
Problems in older homes are often well hidden. More often than not, serious damage doesn't show any symptoms until the damage is significant and exp
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
nsive. There are clues, but even trained eyes sometimes have difficulty telling normal wear and tear from the signs of serious underlying problems.
Most old-home problems, however, have predictable causes and if you know where to loo
Most old-home problems, however, have predictable causes and if you know where to loo
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
you can find hints that might lead you to discover concealed damage. Find the problems early enough and you might be able to fix them relatively easily, or keep yourself from buying into unexpected expensive repairs.
H-2-Oh
H-2-Oh
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
o!
Water is the number one cause of damage in all homes, especially older ones. Look for missing or damaged roof shingles, rotted or loose trim boards, and disconnected or plugged-up gutters and downspouts. Problems with gut
Water is the number one cause of damage in all homes, especially older ones. Look for missing or damaged roof shingles, rotted or loose trim boards, and disconnected or plugged-up gutters and downspouts. Problems with gut
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
ters and downspouts are the biggest cause of water damage - they must be cleaned and checked regularly. If you're looking to buy an older home, check the condition of the gutters and downspouts - they're big clue to finding hidden wat
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
r problems elsewhere in the house.
As the ground around a home settles naturally, it can slope in toward the house and begin directing water at the foundation wall. Modern waterproofing systems can delay the subsequent damage for a w
As the ground around a home settles naturally, it can slope in toward the house and begin directing water at the foundation wall. Modern waterproofing systems can delay the subsequent damage for a w
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
ile, but older homes don't have sophisticated waterproofing systems - if they have any at all. Many very old homes have porous stone foundations that have no ability to repel ground water. Check the grade at the perimeter of the house
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
- settling near the foundation may indicate water in the basement.
Plug It In
When your grandparents' family gathered around the Philco radio in the 1930's listening to the Jack Benny Show they weren't putting much
Plug It In
When your grandparents' family gathered around the Philco radio in the 1930's listening to the Jack Benny Show they weren't putting much
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
of a load on the house's electrical system - the radio and a lamp or two may have been the only electrical appliances in the house.
But now there's a TV in every bedroom; two or three computers; dozens of light fixtures; and a whole
But now there's a TV in every bedroom; two or three computers; dozens of light fixtures; and a whole
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
itchen full of modern electrical conveniences. The appliances have grown - has the electrical system kept pace?
Each fixture or appliance "draws" power from outside in the form of amps; the more fixtures, the more amperage r
Each fixture or appliance "draws" power from outside in the form of amps; the more fixtures, the more amperage r
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
quired. If the fixtures need more amps than the electrical system is rated for, the system can overheat, spark, or fail entirely - all potential fire hazards. Any home over 40 years old is a likely candidate for having an outdated ele
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
trical system. Check the electrical panel for the amperage rating - modern homes require at least 100 amps and many require much more. Older homes may have "fuseboxes" rated for 60 amps or less. Check any visible wiring to see if it's
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
made of aluminum, which is also considered a fire hazard and was discontinued decades ago.
Look around the house - are there lots of extension cords and plug adapters? Are there "burn marks" around some switches and outlets? Are the
Look around the house - are there lots of extension cords and plug adapters? Are there "burn marks" around some switches and outlets? Are the
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
e rooms without any outlets at all? Replacing an electrical system to remove safety risks or to bring the system up to current codes can be a very expensive project.
Home Sweet (Old) Home
If you own an old house, ke
Home Sweet (Old) Home
If you own an old house, ke
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
p up with the maintenance to prevent costly repairs. If you're thinking about buying one, check carefully for the signs of hidden damage and unsafe conditions first - a little detective work might keep you from saying "Yikes!" one day
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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