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If you are a sports enthusiast, you probably know that the best offensive team does not necessarily win the championship. Instead, it

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

is normally the best defensive team that will come out on top. Of course, to score - you need offense. But with a solid defense, yo

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

do not need to score very often to win. As long as your team does not concede any points, then you cannot lose – a draw is the best

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

our opposition can do against your team.

What has this got to do with anything in trading? The same principle holds in trading. All

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

traders are excited about making money – most do not think about protecting their investment. Defense or stop loss is necessarily to

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

protect what you have and risks have to be carefully analyzed to ensure that your odds of success is high. A good defense will limit

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

nd minimize your losses – making it easy for you to recover from this minor setback.

In many ways, sports and trading have this simil

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

arity. In sports, when your team is behind, the players will be motivated to attack and also take more risks that will leave the defe

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

se vulnerable. In trading, same – when you lose, you will be thinking of getting back your capital by taking more aggressive position

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

. Sometimes, trade even when there are no good trading opportunities.

The harder you try to get back into the game the worst it beco

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

es. As trader, we have all been through this unfortunate path before. This becomes dangerous because taking aggressive positions mad

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

e through emotional decision making will cause even more damage to your portfolio. While this could provide the adrenaline rush and t

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

e excitement, it definitely will not provide any help to your financial well-being.

When you understand that you can prevent taking b

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

g financial loss (in any venture), this is when you will start to see your assets grow. The only way to protecting what you have is t

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

o organize a strong, non-compromising defensive line-up. This defense will ensure that you will always be in the game.

Every time yo

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

look at a trade – think of your defense first before thinking of your profit. Eventually this will set the discipline in you. This

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

imple rule will keep you in the world of investing for a long time. Capital preservation is key to your survival in the investing gam

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

e or any business. Build a good defense and you might be pleasantly surprised how easy it is to profit from the market.

Get your gam

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

plan together - weigh the risk and challenges that you face. By looking at the big picture, you can gather enough information to com

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

up with an intelligent defensive strategy. A strong defense will keep you from going out of business.

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tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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