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Unit trusts (UTs) are a form of pooled investment but are quite different from investment trusts (ITs).

They consist of a portfolio of s

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

hares managed by a professional company but owned separately by a trust.

The price of a unit is the total value of the underlying invest

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ents divided by the number of units. Units may be income (income is paid out) or accumulation (income is reinvested).

Units are bought a

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

nd sold at varying prices, like shares, any margin between the two being an initial charge which may he as high as 5%. In some cases ther

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

is an exit charge instead, which reduces over a period, perhaps to nothing after five years.

There is also an annual charge in the form

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

of a management fee, usually 1-2% of the fund value.

UTs have a similar variety of investing areas to ITs. Of particular interest may be

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

corporate bond funds, especially those targeted at high yield bonds.

It must be remembered that the capital value of corporate bond fun

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

s is affected by changes in market interest rates a rise in rates means a fall in value and vice versa. High yield bonds often include f

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

reign company bonds and so are also subject to exchange rate fluctuations.

UTs do not have the facility for gearing and cannot be at a d

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

iscount or premium to the underlying investments, so tend to be less volatile.

Many PEPs and ISAs are set up by unit trust managers spec

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

fically for investing in their range of UTs and there is a lot to be said in favour of pooled investing in equities.

Advisers get an ini

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ial commission, so it is worth asking for a rebate, which some offer in their literature - they are called discount brokers. They also ge

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

t a small annual commission (usually 0.5%). As these commissions cannot be avoided by investing direct it is worth using a discount broke

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

, who may also provide annual or half yearly statements, possibly with useful performance comparisons.

Information about UTs can be obta

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ned from the Association of Unit Trusts.

Open ended investment companies

Unit trusts are a singularly British institution and ma

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ny are converting to the continental style open ended investment company (OEIC), which have only one price for buying and selling, with s

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

parate charges. As they are companies, the 'units' are actually shares.

However, there is a proposal that single pricing should become c

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

mpulsory for unit trusts.

Fund supermarkets

There are fund 'supermarkets' or 'networks', where the provider offers (usually over

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

the Internet) a number of pooled investments to choose from, with easy (and cheap) transfers between the funds. They are frequently disc

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

unt supermarkets, with lower initial charges.

Some providers offer a much wider choice than others, so again here it pays to shop around

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Answers - Investing in Pooled Equity Funds - Unit Trusts

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